Professor Deng is a Postdoctoral fellow of the Sanit-Louis Medical School of the University of Paris, France (Professor E-Gluckman, Academician of the French Academy of Sciences, Associate Research Fellow, Department of Surgery, University of Utah Medical School, Senior Visiting Scholar, Department of Orthopaedics, Hopkins University Hospital, USA. Deputy Director of the Society of Physiology and Immunology, National Natural Science Foundation, Guangdong Provincial Natural Science Fund, Beijing Natural Science and other fund review experts. He is the former Director of the Department of Pathophysiology, Department of Pathophysiology, Medical College of Sun Yat-sen University, and Deputy Director of the Center for Translational Medicine, the First Affiliated Hospital of Sun Yat-sen University.
He has presided over 5 National Natural Science Fund projects and 15 other provincial and ministerial level projects and has published more than 100 papers. As a communication author, he has published more than 40 SCI papers with a total impact factor of more than 140 points. Professor Deng has obtained two invention patents. He was awarded six national and provincial scientific research awards. In 1998, he was awarded the second prize of Shanghai Science and Technology Progress Award (mainly completed person). In 2004, he won the first prize of Science and Technology Progress Award of the Ministry of Education. Professor Deng in charge won the second prize of Guangdong Science and Technology Progress Award in 2002 and won the second prize of Nanzhou Excellent Paper Innovation in 2007. In 2010, he was awarded the most prize by Brain Research. He is the editor-in-chief of "Introduction to Medical Research" and "Pathophysiology". He also takes parts in Zhonghua Medical Awards Jury and Guangdong Science and Technology Awards Judge penal.
Professor Deng’s research interests include stem cell transplantation for the treatment of nerve damage, cardiovascular and cerebrovascular diseases and rheumatism, basic and clinical application of orthopedics and nerve repairment.
Publication:
1. Ruirui Yang(#), Caixia Xu(#), Tao Wang, Yuanqi Wang, Jingnan Wang, Daping Quan (*) and David Y. B. Deng (*). PTMAc-PEG-PTMAc hydrogel modified by RGDC and hyaluronic acid promotes neural stem cells' survival and differentiation in vitro. RSC Advances. 2017,7,41098-41104.
2. Yingling Miao(#), Ruirui Yang, David YB Deng (*), and Li-Ming Zhang (*), 1Poly(L-lysine) modified zein nanofibrous membranes as efficient scaffold for adhesion, proliferation and differentiation of neural stem cells. RSC ADV, 2017.7.17711-17719.
3. Hongwu Zhang(#), Liqin Wang, Shihong Wen, Qingfeng Xiang, Xianhong Xiang, Caixia Xu, Yong Wan , Jingnan Wang, Bin Li, Yiqian Wan, Zhiyun Yang, David Y.B. Deng (*), Magnetic resonance imaging tracking and assessing repair function of the bone marrow mesenchymal stem cells transplantation in a rat model of spinal cord injury . Oncotarget. 2017; 8:58985-58999.
4. Jingnan Wang(#), Jiayun Tan(#), Jiahao Luo, Peilin Huang, Wuyi Zhou, Luming Chen, Lingli Long, Li‑ming Zhang, Banghao Zhu, Liqun Yang（*） and David Y. B. Deng(*) . Enhancement of scutellarin oral delivery efcacy by vitamin B12-modifed amphiphilic chitosan derivatives to treat type II diabetes induced-retinopathy . J Nanobiotechnology. 2017 Mar 01 ;15(1).
5. Minghua Lai(#), Jingnan Wang(#), Jiayun Tan, Jiahao Luo, Li-Ming Zhang, David Y. B. Deng(*), Liqun Yang(*). Preparation, complexation mechanism and properties of nano-complexes of Astragalus polysaccharide and amphiphilic chitosan derivatives . Carbohydrate Polymers 2017.03.04,161:261-269.
6. Ningning Chen(#), Jingsheng Cen, Jingnan Wang, Gangjian Qin, Lingli Long, Le Wang, Fuxin Wei, Qingfeng Xiang, David Deng(*), yong wan(*), Targeted inhibition of LINGO-1 in transplanted neural stem cells promotes neuronal differentiation and functional recovery in rats subjected to spinal cord injury. Critical Care Medicine , 2016 Mar;44(3):e146-57.
7. Jue Wang(#) , Zhizhong Ye(#); Shuhui Zheng; Luming Chen; Yong Wan(*) ; Yubin Deng(*); Ruirui Yang. Lingo-1 shRNA and Notch signaling inhibitor DAPT promote differentiation of neural stem/ progenitor cells into neurons Brain Research 2016 Mar 1;1634:34-44.
8. Lingli Long(#), Jingnan Wang(#), Ningning Chen, Shuhui Zheng, Lanying Shi, Yuxia Xu, Canqiao Luo(*), Yubin Deng(*).Curcumin Ameliorates Reserpine-Induced Gastrointestinal Mucosal Lesions Through Inhibiting IκB-α/NF-κB Pathway and Regulating Expression of Vasoactive Intestinal Peptide and Gastrin in Rats. J Med Food. 2016 Jun;19(6):528-534.
9. Huang C, Zheng H, He W, Lu G, Li X, Deng Y(*), Zeng M(*). Ghrelin ameliorates the human alveolar epithelial A549 cell apoptosis induced by lipopolysaccharide. Biochem Biophys Res Commun. 2016 May 20;474(1):83-90.
10. Fang Liu(#),Jingnan Wang,Qingyun Cao,Haidong Deng,guang shao,David Y. B. Deng(*)andWuyi Zhou(*). One-step synthesis of magnetic hollow mesoporous silica (MHMS) nanospheres for drug delivery nanosystems via electrostatic self-assembly templated approach. Chem Commun (Camb). 2015 11;51(12):2357-60.
11. He T(#), Wang J(#), Huang P, Zeng B, Li H, Cao Q, Zhang S, Luo Z, Deng DY(*), Zhang H(*), Zhou W(*). Electrospinning polyvinylidene fluoride fibrous membranes containing anti-bacterial drugs used as wound dressing. Colloids Surf B Biointerfaces. 2015 Jun 1;130:278-86.
12. Peilin Huang(#), Jingnan Wang(#), Shuting Lai, Fang Liu, yubin Deng (*), Wuyi Zhou(*). Surface modified titania nanotubes containing antibacterial drugs for controlled delivery nanosystems with high bioactivity. Journal of Materials Chemistry B. 2014,2, 8616-8625.
13. Fang Liu(#), Hongwu Zhang, Qingyun Cao, yubin Deng(*), Wuyi Zhou(*). High-efficiency loading in small mesopores (2–3 nm) forming a matrix type controlled drug delivery nanosystem . RSC Advances. 2014.4(17).8918-8921.
14. Zhang HW(#), Wang LQ, Xiang QF, yubin Deng(*). Specific lipase-responsive polymer-coated gadolinium nanoparticles for MR imaging of early acute pancreatitis. Biomaterials. 2014.35(1).356-67.
15. Liang X(#), Ren X, Liu Z, Liu Y, Wang J, Wang J, Zhang LM, Deng DY(*), Quan D, Yang L(*). An efficient nonviral gene-delivery vector based on hyperbranched cationic glycogen derivatives. Int J Nanomedicine. 2014 31;9:419-35.
16. Cen JS(#), Wu HF, Wang J, Ren XY, Zhang HW, Wang JN, Deng YB(*), Wan Y(*). Local injection of lentivirus encoding LINGO-1 shRNA promotes functional recovery in rats with complete spinal cord transaction. Spine. 2013.38(19).1632-1639.
17. YE ZhiZhong , YE WeiBiao , WANG Jue, ZHOU GuangQian, ZHANG XiuQuan, Deng Yubin(*). HIF-1-modified BMSCs improve migration and reduce neuronal apoptosis after stroke in rats. Chinese Science Bulletin. 2013.58(28-29).3519-3528.
18. Wu HF(#), Cen JS, Zhong Q, Chen LM, Wang J, Yong Wan(*), yubin Deng(*). The promotion of functional recovery and nerve regeneration after spinal cord injury by lentiviral vectors encoding Lingo-1 shRNA delivered by Pluronic F-127. Biomaterials. 2013.34(6).1686-700.
19. Shi-Jing Mo(#), Qian Zhong(#), Yan-Fang Zhou, David B Deng(*), Xiu-Quan Zhang. Bone marrow-derived mesenchymal stem cells prevent the apotosis of neuro-like PC12 cells via erythropoietin expression. Neuroscience Letters. 2012， 522(2):92-97.
20. Zhou Yanfang(#), Yang Bin, Ren Xianyue, yubin Deng(*), Liqun Yang(*). Hyperbranched cationic amylopectin derivatives for gene delivery. Biomaterials .2012. 33(18).4731-4740.
21. Qian Zhong(#), Yanfang Zhou(#), Weibiao Ye, Tuo Cai, Xiuquan Zhang, yubin Deng(*). Hypoxia-inducible factor 1-α-AA-modified bone marrow stem cells protect PC12 cells from hypoxia-induced apoptosis, partially through VEGF/PI3K/Akt/FoxO1 pathway. Stem Cells Dev. 2012. 21(14). 2703-17.
22. Yu Liu(#), Zhi-Jie He, Bo Xu, Qi-Zhu Wu, Gang Liu, Hongyan Zhu, Qian Zhong, yubin Deng(*), Hua Ai, Qiang Yue. Evaluation of Cell Tracking Effects for Transplanted Mesenchymal Stem Cells with jetPEI/Gd-DTPA Complexes in Animal odels of Hemorrhagic Spinal Cord Injury . Brain Research .2011.19(1391).24-35.
23. Xiao-ai Chen(#),Lijun Zhang, Weiwei Wang, Bo Xu, Zhijie He, Qian Zhong, Xintao Shuai, Liqun Yang. yubin Deng(*). Plasmid Encapsulated Polyethylene Glycol Grafted Polyethylenimine Nanoparticles for Gene Delivery into Rat Mesenchymal Stem Cells". International Journal of Nanomedicine. 2011.6.843-53.
24. Deng Junjie(#), Zhou Yanfang, Xu Bo, Mai Kaijin, yubin Deng(*), Li-Ming Zhang(*). Dendronized chitosan derivative as a biocompatible gene delivery carrier. Biomacromolecules.2011.12(3).642-9.
25. Yu Liu(#), Zhi-Zhong Ye,Wang YaZhu, yubin Deng(*). Induction-dependent neural marker expression and electrophysiological characteristics of bone marrow mesenchymal stem cells naturally express nestin. Chinese Science Bulletin . 2011.56(1).1-7.
26. Yubin Deng(#) (*)，Weibiao Ye，Zhenzhen Hu，Ying Yan，Ye Wang，Bekomson Francis Takon，Guangqian Zhou，Yanfang Zhou. Intravenous bone marrow stromal cell therapy promotes endogenous cell proliferation after stroke in rat. Neurological Research. 2010 .32(2).148-56.
27. Biyan Lu(#), Zhizhong Ye, yubin Deng (*), Hongfu Wu, Jianqiang Feng. MEK/ERK pathway mediates cytoprotection of salvianolic acid B against oxidative stress-induced apoptosis in rat bone marrow stem cells. Cell Biol Int.2010.34(11).1063-8.
28. ShiYong Li(#), JianQiang Feng, yubin Deng (*), WeiBiao Ye. Oxidative preconditioning promotes bone marrow stromal cells migration and prevents apoptosis. Cell Biology International. 2009.33(3).411-8.
29. Bi XB(#), Gan DH, yubin Deng (*), Wang YZ. Salvianolic acid B promotes survival of transplanted mesenchymal stem cells in spinal cord-injured rats. Acta Pharmacolo Sin.2008.29(2).169-176.
30. Y Liu, Zhu WB, Bi XB, Wang YZ, Ye MH, Zhou GQ, yubin Deng(#)(*). The co-transplantation of human bone marrow stromal cells and embryo olfactory ensheathing cells as a new approach to treat spinal cord injury in a rat model. Cytotherapy. 2008.10(6).551-564.
31. Ye Wang(#), Zhou GQ (*), yubin Deng (*). SDF-1/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain in a rat model. Brain research.2008.21(1195).104-12.
Email Address: dengyub@mail.sysu.edu.cn