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潘逸航 副院长、精准医学中心主任、基础医学教研室主任、科研中心常务副主任、临床医学研究大数据中心执行主任、广东省消化系统恶性肿瘤防治研究重点实验室副主任
博士生导师、特聘研究员

个人简介:

中山医科大学临床医学专业学士,美国路易斯安那州立大学医学中心细胞生物学博士、康奈尔大学医学院博士后、美国医学遗传学学院临床Fellow。曾就职于康奈尔大学医学院附属医院病理科6年,从事基因检测、诊断的临床工作。有中美两国的临床实践及医学研究工作经历近30年,在解读与疾病和健康相关的遗传学因素方面有丰富的临床经验。作为一名资深精准医学领域的科学家,潘逸航博士带领其课题组团队致力于精准医学研究。在Advanced MaterialsNature NeuroscienceGutSignal Transduction and Targeted Therapy等国际期刊发表高水平论文30余篇,出版一本医学专业书章节,并担任多个SCI杂志审稿人,主持或参与10余项国家级科研项目,是国家重点研发计划合成生物学专项课题《膀胱癌致病相关基因回路及相互作用网络的机制研究》的课题组组长。担任广东省临床医学会临床规范化培训与管理专委会副主任委员、深圳市医学会人工智能机器人专业委员会副主任委员等。

 

著作

Quick, Q., Pan, Y., and Skalli, O.  Role of Synemin in astrocytoma cell migration.  Chapter in M.A. Hayat (ed.), Tumors of the Central Nervous System, Volume 5, Springer Science+ Business Media B.V. 2012

 

近五年代表性论文:

1. Jia Li#, Leli Zeng#*, Zheng Wang, Hengxing Chen, Shuo Fang, Jinquan Wang, Chao-Yun Cai, Enming Xing, Xinxing Liao, Zhi-Wei Li, Charles R. Ashby Jr, Zhe-Sheng Chen*, Hui Chao*, Yihang Pan*. Cycloruthenated Self-Assembly with Metabolic Inhibition to Efficiently Overcome Multidrug Resistance in Cancers. Advanced Materials, 2022 Jan, 34(1), 2100245. (IF= 30.849一区)

2. Qiangsheng He#, Man Yang, Xiwen Qin, Die Fan, Jinqiu Yuan*, Yihang Pan*. Risk stratification for proton pump inhibitor-associated type 2 diabetes: a population-based cohort study. Gut, 2021 Nov, 70(11), 2212-2213. (IF=23.059一区)

3. Qiangsheng He# , Bin Xia#, Wenbo Meng#, Die Fan, Zi-Chong Kuo, Junjie Huang, Xiwen Qin, Huachun Zou, Yulong He, Changhua Zhang, Shuo Fang, Yihang Pan*, Man Yang*, Jinqiu Yuan*. No Associations Between Regular Use of Proton Pump Inhibitors and Risk of All-Cause and Cause-Specific Mortality: A Population-Based Cohort of 0.44 Million Participants. The American Journal of Gastroenterology, 2021 Nov, 116(11), 2286-2291. (IF=10.864,一区)

4. Man Yang#, Qiangsheng He#, Fang Gao, Krish Nirantharakumar, Tonny Veenith, Xiwen Qin, Amy T Page, Martin C S Wong, Junjie Huang, Zi Chong Kuo, Bin Xia, Changhua Zhang, Yulong He, Wenbo Meng*, Jinqiu Yuan*, Yihang Pan*. Regular use of proton-pump inhibitors and risk of stroke: a population-based cohort study and meta-analysis of randomized-controlled trials. BMC Medicine, 2021 Dec, 19(1), 316.12. (IF=8.775一区)

5. Yuzhi Xu#, Yanfei Zhang, Huihui Yang, Wen Yin, Leli Zeng, Shuo Fang, Si-Yang Liu*, Zong Dai*, Xiaoyong Zou, Yihang Pan*, Two-dimensional coordination polymer-based nanosensor for sensitive and reliable nucleic acids detection in living cells. Chinese Chemical Letters, 2021 July, doi.org/10.1016/j.cclet.2021.07.041. (In press). (IF= 6.779二区)

6. Silpa Narayanan#, Zhuo-Xun Wu#, Jing-Quan Wang#, Hansu Ma, Nikita Acharekar, Jagadish Koya, Sabesan Yoganathan, Shuo Fang*, Zhe-Sheng Chen*, Yihang Pan*. The Spleen Tyrosine Kinase Inhibitor, Entospletinib (GS-9973) Restores Chemosensitivity in Lung Cancer Cells by Modulating ABCG2-mediated Multidrug Resistance. International Journal of Biological Sciences, 2021 Jun, 17(10), 2652-2665. (IF=6.58二区)

7. Zhuo-Xun Wu#, Qiuyan Mai#, Yuqi Yang, Jing-Quan Wang, Hansu Ma, Leli Zeng, Zhe-Sheng Chen*, Yihang Pan*. Overexpression of human ATP-binding cassette transporter ABCG2 contributes to reducing the cytotoxicity of GSK1070916 in cancer cells. Biomedicine & Pharmacotherapy, 2021 Apr, 136, 111223. (IF=6.529二区)

8. Changbo Qu#, Gwenny M Fuhler*, Yihang Pan*. Could Histamine H1 Receptor Antagonists Be Used for Treating COVID-19? International Journal of Molecular Sciences, 2021 May, 22(11), 5672. (IF= 5.923二区)

9. Bin Xia#, Jianjun Peng, De Toni Enrico, Kuiqing Lu, Eddie C Cheung, Zichong Kuo, Qiangsheng He, Yan Tang, Anran Liu, Die Fan, Changhua Zhang, Yulong He*, Yihang Pan*, Jinqiu Yuan*. Metabolic syndrome and its component traits present gender-specific association with liver cancer risk: a prospective cohort study. BMC Cancer, 2021 Oct, 21(1), 1084. (IF=4.430二区)

10. Changbo Qu#, Jaap Keijer, Merel J W Adjobo-Hermans, Melissa van de Wal, Tom Schirris, Clara van Karnebeek, Yihang Pan*, Werner J H Koopman*. The ketogenic diet as a therapeutic intervention strategy in mitochondrial disease. The International Journal of Biochemistry & Cell Biology. 2021 Sep, 138, 106050. (IF=5.085三区)

11. Jun Ju#, Xiuyan Yang#, Jian Jiang#, Dilong Wang , Yumeng Zhang , Xiaofeng Zhao , Xiaoyi Fang , Huanquan Liao , Lei Zheng , Shupeng Li , Sheng-Tao Hou , Liyang Liang, Yihang Pan*, Huiliang Li*, Ningning Li*. Structural and Lipidomic Alterations of Striatal Myelin in 16p11.2 Deletion Mouse Model of Autism Spectrum Disorder. Frontiers in Cellular Neuroscience, 2021 Aug, 15, 718720. (IF=5.505二区)

12. Lang You#, Fengxia Li#, Yan Sun#, Liang Luo, Jian Qin, Tao Wang, Yuchen Liu, Ruogu Lai, Ruohan Li, Xiaoran Guo, Qiuyan Mai, Yihang Pan*, Jianrong Xu*, Ningning Li*. Extract of Acalypha australis L. inhibits lipid accumulation and ameliorates HFD-induced obesity in mice through regulating adipose differentiation by decreasing PPARγ and CEBP/α expression. Food & Nutrition Research, 2021 Mar, 65. (IF=3.894二区)

13. Jinqiu Yuan#, Yanhong Jessika Hu, Jie Zheng, Jean Hee Kim, Tim Sumerlin, Youpeng Chen, Yulong He, Changhua Zhang, Jinling Tang, Yihang Pan*, Michael Moore*. Long-term use of antibiotics and risk of type 2 diabetes in women: a prospective cohort study. International Journal of Epidemiology, 2020 Oct, 49(5), 1572-1581. (IF=7.196, 一区)

14. Yihang Pan#, Meiqi Xin#, Changhua Zhang#, Willa Dong, Yuan Fang, Wenhui Wu, Mingzhe Li, Jun Pang, Zilong Zheng, Zixin Wang#*, Jinqiu Yuan#, Yulong He#. Associations of Mental Health and Personal Preventive Measure Compliance With Exposure to COVID-19 Information During Work Resumption Following the COVID-19 Outbreak in China: Cross-Sectional Survey Study. Journal of Medical Internet Research, 2020 Oct, 22(10), e22596. (IF=5.428, 二区)

15. Yihang Pan#, Yuan Fang#, Meiqi Xin, Willa Dong, Liemin Zhou, Qinghua Hou, Fanping Li, Gang Sun, Zilong Zheng, Jinqiu Yuan#, Zixin Wang#, Yulong He#*. Self-Reported Compliance With Personal Preventive Measures Among Chinese Factory Workers at the Beginning of Work Resumption Following the COVID-19 Outbreak: Cross-Sectional Survey Study. Journal of Medical Internet Research, 2020 Sep, 22(9), e22457.(IF=5.428, 二区)

16. Jinqiu Yuan#, Changhua Zhang#, Jeffrey A Sparks, Susan Malspeis , Kelvin Kam-Fai Tsoi , Jean H Kim , Benjamin A Fisher , Fang Gao , Tim Sumerlin , Yan Liu , Yuxing Liu , Yihang Pan*, Yulong He*, Joseph J Y Sung. Regular use of proton pump inhibitor and risk of rheumatoid arthritis in women: a prospective cohort study. Alimentary Pharmacology & Therapeutics, 2020 Aug, 52(3), 449-458. (IF=8.171, 一区)

17. Yun Chen#, Yao Guo#, Yihang Pan*, Zhizhuang Joe Zhao*. Structure analysis of the receptor binding of 2019-nCoV. Biochemical and Biophysical Research Communications, 2020 Feb, 525(1), 135–40.(IF=3.575, 三区)

18. Bin Xia#, Qiang-Sheng He#, Yihang Pan#, Fang Gao, An-Ran Liu, Yan Tang, Charing Chong, Anthony Y. B. Teoh, Fang-Ping Li, Yulong He*, Changhua Zhang*, Jin-Qiu Yuan*. Metabolic syndrome and risk of pancreatic cancer: A population-based prospective cohort study. International Journal of Cancer, 2020 Dec, 147(12), 3384-3393. (IF=7.396, 一区)

19. Dilong Wang#, Qiuyan Mai#, Xiuyan Yang#, Xinjin Chi, Ruohan Li, Jian Jiang, Liang Luo, Xiaoyi Fang, Peng Yun, Liyang Liang, Guang Yang, Kun Song, Liang Fang, Yun Chen, Ying Zhang, Yulong He, Ningning Li*, Yihang Pan. Microduplication of 16p11.2 locus Potentiates Hypertrophic Obesity in Association with Imbalanced Triglyceride Metabolism in White Adipose Tissue. Molecular Nutrition & Food Research, 2022 Jan, 2100241. (IF=5.914二区)

20. Hanna Foster#, E Josue Ruiz#, Christopher Moore, Gordon W H Stamp, Emma L Nye, Ningning Li, Yihang Pan, Yulong He, Julian Downward, Axel Behrens*. ATMIN Is a Tumor Suppressor Gene in Lung Adenocarcinoma. Cancer Research, 2019 Oct, 79(20), 5159-5166. (IF=12.701二区)

21. Ningning Li#, Roya Babaei-Jadidi#, Federica Lorenzi#, Bradley Spencer-Dene, Philip Clarke, Enric Domingo, Eugene Tulchinsky, Robert G J Vries, David Kerr, Yihang Pan, Yulong He, David O Bates, Ian Tomlinson, Hans Clevers, Abdolrahman S Nateri*. An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance. Oncogenesis, 2019 Feb, 8(3), 13. (IF=7.485, 一区)

22. Yubin Huang#, Zhen Xu#, Shanshan Xiong, Fangfang Sun, Guangrong Qin, Guanglei Hu, Jingjing Wang, Lei Zhao, Yu-Xiang Liang, Tianzhun Wu, Zhonghua Lu, Mark S Humayun, Kwok-Fai So, Yihang Pan, Ningning Li, Ti-Fei Yuan*, Yanxia Rao*, Bo Peng*. Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion. Nature Neuroscience, 2018 Apr, 21(4), 530-540. (IF=20.071, 一区)

23. Xibo Li#, Ningning Li#, Kastytis Sidlauskas, Houli Li, Chao Zhang, Mingli Peng, Qinlu Zhang, Kai Hua, Lili Guo, Fuqiang Li, Ying Zhang, Mingwei Chen, Guanjun Zhang, Yihang Pan, Linlin Gao, Yali Cui*. Doxorubicin-Loaded Dextran-Modified GoldMag Nanoparticles for Targeting Hepatocellular Carcinoma. Journal of Biomedical Nanotechnology, 2018 Jun, 14(6), 1135-1146. (IF=4.099二区)

24. Yun Chen, Yihang Pan, Yao Guo, Wanke Zhao, Wanting Tina Ho, Jianlong Wang, Mingjiang Xu, Feng-Chun Yang, Zhizhuang Joe Zhao*. Tyrosine kinase inhibitors targeting FLT3 in the treatment of acute myeloid leukemia. Stem Cell Investigation, 2017 Jun, 4, 48.

25. Liqiu Liao#, Mei Song#, Xin Li, Lili Tang, Tuo Zhang, Lixing Zhang , Yihang Pan, Lotfi Chouchane, Xiaojing Ma*. E3 Ubiquitin Ligase UBR5 Drives the Growth and Metastasis of Triple-Negative Breast Cancer. Cancer Research, 2017 Apr, 77(8), 2090-2101. (IF=12.701, 一区)

26. Daniel A Luedtke#, Xiaojia Niu#, Yihang Pan, Jianyun Zhao, Shuang Liu, Holly Edwards, Kang Chen, Hai Lin, Jeffrey W Taub*, Yubin Ge*. Inhibition of Mcl-1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. Signal Transduction and Targeted Therapy, 2017 Apr, 2, 17012. (IF=18.187, 一区)

出诊信息