个人简介：
华中科技大学同济医学院临床六年制德语班（学士），华中科技大学同济医院神经内科硕博连读（PhD），德国Tübingen大学医学博士（MD）。法国巴黎法兰西学院 (Collège de France)、法国科学院(CNRS)博士后，新加坡国立大学生命研究中心Senior Research Fellow。
2018年底回国成为独立PI，2019年7月建立实验室（https://chenjuyilab.com），从事胶质细胞在中枢神经系统疾病中的作用及其作为治疗新靶点的研究。发表SCI论文100余篇，其中以一作/通讯作者（含共同）在Science Translational Medicine（2025）、Nature Communications（2025）、Brain（2025、2022封面）、Neuron（2023封面）、Trends in Neurosciences（2023）、The EMBO Journal（2021）等发表60余篇。出版专著《Physiology and Pathophysiology of Oligodendroglia》1部（第一主编）。
先后获批国家自然科学基金青年项目1项、国家自然科学基金面上项目3项、部省级项目2项、市校级项目6项。先后入选广东省“杰青”、深圳市“杰青”及“优青”、深圳市海外高层次人才、中山大学“百人计划”。担任Acta Physiologica、Journal of Inflammation、Stem Cell Reviews and Reports等杂志编委、中国神经科学学会胶质细胞分会青年委员、2025年第17届欧洲胶质细胞大会组委会委员。
代表性论文：
- Shujun Peng, Hui Chen, Guowei Yin*, Alexei Verkhratsky*, Chenju Yi*. Phase separation in neurodegenerative disorders: a metabolic perspective on protein aggregation and therapeutic targeting. Translational Neurodegeneration. (EPub date: 2026/08/31)(PMID: 42675502) (最后通讯)
- Jie Jiao, Hui Chen, Alexei Verkhratsky*, Yixun Su*, Chenju Yi*. Mitochondria transfer in neurological disorders: the key role of neuroglia. Molecular Neurodegeneration. (EPub date: 2026/05/21)(PMID: 42169139) (最后通讯)
- Arthur Butt*, Jianqin Niu*, Chenju Yi*, Alexei Verkhratsky*. Physiology of oligodendroglia, Physiological Reviews. 2026, 106 (3), 1837-1911. (并列通讯排第二)
- Yixun Su, Hui Li, Wenjie Zhang, Shi Tao, Qi Wang, Xuan Zhang, Mi Zhou, Xiaomin Huang, Chenmeng Wang, Yong Tang, Hui Chen, Alexei Verkhratsky, Zhengbao Zha*, Jianqin Niu* Chenju Yi*. Connexin43 hemichannel blockade turns microglia neuroprotective and mitigates cognitive deficits in a mouse model of amyloidosis. Nature Communications. 2025/07/01 (最后通讯)
- Qi Wang, Taida Huang, Zihan Zheng, Yixun Su, Zhonghao Wu, Cong Zeng, Guangdan Yu, Yang Liu, Xiaorui Wang, Hui Li, Xiaoying Chen, Zhuoxu Jiang, Jinyu Zhang, Yuan Zhuang, Yi Tian, Qingwu Yang, Alexei Verkhratsky, Ying Wan*, Chenju Yi*, Jianqin Niu*. Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis. Science Translational Medicine. 2025/04/02 (并列通讯排第二)
- Yang Yang, Hui Chen, Shuwen Huang, Hao Chen, Alexei Verkhratsky, Jianqin Niu*, Yibo Qu*, Chenju Yi*, BOK-engaged mitophagy alleviates neuropathology in Alzheimer’s disease, Brain, 2025 Feb. (最后通讯)
- Yixun Su, Alexei Verkhratsky*, Chenju Yi*，Targeting connexins: possible game changer in managing neuropathic pain? Trends in Molecular Medicine, 2024 July, 30(7):642-659. (最后通讯，封面文章)
- Xiaomin Huang#, Junhua Qi#, Yixun Su#, Ying Zhou, Qi Wang, Taida Huang, Dongdong Xue, Yunxin Zeng, Alexei Verkhratsky, Benjie Zhou*, Hui Chen, Chenju Yi*，Endothelial DR6 in blood-brain barrier malfunction in Alzheimer's disease, Cell Death&Disease, 2024 Apr 12;15(4):258. (最后通讯)
- Chenju Yi*, Alexei Verkhratsky*, Jianqin Niu*, Pathological potential of oligodendrocyte precursor cells: Terra Incognita, Trends in Neurosciences, 2023 July, 46(7):581-596. (一作兼通讯)
- Yixun Su, Xiaorui Wang, Yujian Yang, Liang Chen, Wenlong Xia, Kimberly K. Hoi, Hui Li, Qi Wang, Guangdan Yu, Xiaoying Chen, Shouyu Wang, Yuxin Wang, Lan Xiao, Alexei Verkhratsky, Stephen Fancy*, Chenju Yi*, Jianqin Niu*, Astrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during neocortical development, Neuron, 2023, 111(2): 190-201. (并列通讯排第二，封面文章)
- Qi Wang†, Xiaomin Huang†, Yixun Su, Guowei Yin, Shouyu Wang, Bin Yu, Hui Li, Junhua Qi, Hui Chen, Wen Zeng, Kai Zhang, Alexei Verkhratsky*, Jianqin Niu*, Chenju Yi*, Activation of Wnt/β-catenin pathway mitigates blood-brain barrier dysfunction in Alzheimer’s disease, Brain, 2022, 145(12): 4474-4488. (最后通讯，封面文章)
- Chenju Yi; Ket Yin Goh; Lik-Wei Wong; Ajeena Ramanujan; Kazuhiro Tanaka; Sreedharan Sajikumar; Carlos F. Ibanez*; Inactive variants of death receptor p75NTR reduce Alzheimer’s neuropathology by interfering with APP internalization, The EMBO Journal, 2021, 40(2): e104450. (独立一作)
出版专著:
Editors: Chenju Yi, Arthur Butt, Alexei Verkhratsky, Jianqin Niu. 《Physiology and Pathophysiology of Oligodendroglia》, Springer Nature Publisher (EPub date: 2025/06/12) 第一主编
个人联系邮箱:
Email：yichj@mail.sysu.edu.cn