个人简介:
中山大学硕士生导师,副研究员,中山大学“百人计划”中青年杰出人才(海外引进高层次人才),广东省精准医学应用学会精准检测分会常务委员。博士毕业于中山大学中山医学院病原生物学专业,曾任杜克大学医学院高级研究员。主要研究方向:肿瘤代谢免疫和传染病防治研究。主持省部级以上课题4项和深圳市科创委面上项目1项,主编学术专著1部,获得国家科技成果1项、广东省科学技术奖励二等奖1项。已申请美国PCT专利1项,中国发明专利5项(已授权2项),软件著作权4项(已获批2项)。累积发表SCI论文30余篇,包括Cell Metabolism, Molecular Cell,JOURNAL OF EXPERIMENTAL MEDICINE,STAR Protocols等学术期刊。iMeta系列期刊、《检验医学与临床》、《热带医学》青年编委。iMeta、Oncogene等期刊审稿人。
主要科研论文:
1. Shen L#, He Y#, Wang K#, Zhang Z, Wen Y, Ma H, Li F, Xia B*, Lin X*, Chen T*. Clinical and molecular epidemiology of type 2 diabetes mellitus-associated intestinal Staphylococcus aureus colonization. Microbiol Spectr. 2026 Sep 25:e0178926.
2. He Y#, Yang H#, Liao C, Ou X, Yang K, Ding T, Zhou X, Liu X, Liu S, Zhou Z*, Chen T*. Phenotypic and genomic characterization of NDM-producing Escherichia coli colonizing the pediatric gut in Shenzhen, China. Microbiol Spectr. 2026 Apr 7;14(4):e0332925.
3. He Y, Chen T*. Draft genome sequences analyses of 25 NDM-producing Escherichia coli isolates from pediatric gut samples in Shenzhen, China. Microbiol Resour Announc. 2026 May 7;15(5):e0014726.
4. Chen T, Lin HK. Protocol to analyze the role of various metabolites in impacting global RNA 5-methylcytosine levels in cultured cells by dot blot. STAR Protocols 2024 Jan 4;5(1):102815..
5. Chen T, Xu ZG, Luo J, Manne RK, Wang Z, Hsu CC, Pan BS, Cai Z, Tsai PJ, Tsai YS, Chen ZZ, Li HY, Lin HK. NSUN2 is a glucose sensor suppressing cGAS/STING to maintain tumorigenesis and immunotherapy resistance. Cell Metab. 2023 Aug 3:S1550-4131(23)00267-X.
6. Chen T#, Jiang H#, Sun H, Xie Z, Ren P, Zhao L, Dong H, Shi M, Lv Z, Wu Z, Li X, Yu X, Huang Y*, Xu J*. Sequence analysis and characterization of pyruvate kinase from Clonorchis sinensis, a 53.1-kDa homopentamer, implicated immune protective efficacy against clonorchiasis. Parasit Vectors. 2017 Nov 9;10(1):557.
7. Tang Z#, Sun H#, Chen T#, Lin Z, Jiang H, Zhou X, Shi C, Pan H, Chang O, Ren P, Yu J, Li X, Xu J, Huang Y, Yu X*. Oral delivery of Bacillus subtilis spores expressing cysteine protease of Clonorchis sinensis to grass carp (Ctenopharyngodon idellus): Induces immune responses and has no damage on liver and intestine function. Fish Shellfish Immunol. 2017 Mar 18;64:287-296.
8. Jiang H#, Chen T#, Sun H, Tang Z, Yu J, Lin Z, Ren P, Zhou X, Huang Y, Li X, Yu X*. Immune response induced by oral delivery of Bacillus subtilis spores expressing enolase of Clonorchis sinensis in grass carps (Ctenopharyngodon idellus). Fish and Shellfish Immunology. 2017 Jan;60:318-325.
9. Yu J#, Chen T#, Xie Z, Liang P, Qu H, Shang M, Mao Q, Ning D, Tang Z, Shi M, Zhou L, Huang Y, Yu X*. Oral delivery of Bacillus subtilis spore expressing enolase of Clonorchis sinensis in rat model: induce systemic and local mucosal immune responses and has no side effect on liver function. Parasitol Res. 2015 Jul;114(7):2499-505.
10. Chen W#, Ning D#, Wang X#, Chen T#, Lv X, Sun J, Wu D, Huang Y, Xu J*, Yu X*. Identification and characterization of Clonorchis sinensis cathepsin B proteases in the pathogenesis of clonorchiasis. Parasit Vectors. 2015 Dec 21;8(1):647.
11. Chen T#, Yu J#, Tang Z, Xie Z, Lin Z, Sun H, Wan S, Li X, Huang Y*, Yu X*, Xu J*. Advanced Enzymology, Expression Profile and Immune Response of Clonorchis sinensis Hexokinase Shows Its Application Potential for Prevention and Control of Clonorchiasis. PLoS Negl Trop Dis. 2015 Mar 23;9(3):e0003641.
12. Chen T, Ning D, Sun H, Li R, Shang M, Li X, Wang X, Chen W, Liang C, Li W, Mao Q, Li Y, Deng C, Wang L, Wu Z, Huang Y*, Xu J*, Yu X*. Sequence analysis and molecular characterization of Clonorchis sinensis hexokinase, an unusual trimeric 50-kDa glucose-6-phosphate-sensitive allosteric enzyme. PLoS ONE 9(9): e107940.
13. Chen T, Huang Y, Yu X*. Serious challenge and thinking of clonorchiasis. Chin J Dis Control Prev. 2016,20(1):1-4,12. (in Chinese)
14. Chen T, Yu X*. Pregnancy with listeria infection. Chin J Obstet Emerg. 2015 May,4(2):105-109. (in Chinese)
个人邮箱:
chentj7@mail.sysu.edu.cn, chentingjin@sysush.com