个人简介：

中山大学附属第七医院科研中心副研究员，硕士生导师，广东省杰出青年，深圳市海外高层次人才。浙江大学学士，新加坡国立大学博士。2019年回国加入中山大学附属第七医院易陈菊课题组进行博士后研究工作。2024年4月转聘为副研究员。研究方向为神经胶质细胞包括星形胶质细胞、少突胶质细胞、和小胶质细胞等在生理与疾病中的作用。获国自然青年基金1项，广东省项目3项，深圳市面上基金1项，深圳市优秀科技创新人才-博士启动项目1项，深圳市医科院项目1项。共发表SCI论文35篇，其中第一/通讯作者研究论文15篇，研究成果主要发表在Neuron, Nature Communications, Trends in Molecular Medicine, Molecular Psychiatry, Brain, Advanced Science, Neuroscience bulletin等杂志上。2021年获欧洲胶质细胞大会青年科学家奖。

教育背景：

2014/08-2019/03 新加坡国立大学   基础医学   博士

2010/09-2014/06 浙江大学             生物科学   学士

工作经历：

2024/04-至今       中山大学附属第七医院，科研中心，副研究员

2021/08-2024/04 中山大学附属第七医院，科研中心，助理研究员

2019/08-2021/07 中山大学附属第七医院，科研中心，博士后

主要研究方向:

1. 神经发育与神经退行性疾病。

2. 神经胶质细胞与神经元在疾病中的互作。

3. 胶质细胞连接蛋白的生理病理功能机制。

代表论文： (^#为第一/共同第一作者，*为通讯/共同通讯作者)

2026

1. Jie Jiao, Hui Chen, Alexei Verkhratsky*, Yixun Su*, Chenju Yi*. Mitochondria transfer in neurological disorders: the key role of neuroglia. Molecular Neurodegeneration. 2026 May 21;21(1). doi: 10.1186/s13024-026-00953-1 (IF=19.6，并列通讯)

2025

2. Yixun Su, Hui Li, Wenjie Zhang, Shi Tao, Qi Wang, Xuan Zhang, Mi Zhou, Xiaomin Huang, Chenmeng Wang, Yong Tang, Hui Chen, Alexei Verkhratsky, Zhengbao Zha*, Jianqin Niu*, Chenju Yi*. Connexin43 hemichannel blockade turns microglia neuroprotective and mitigates cognitive deficits in a mouse model of amyloidosis. Nature Communications. 2025 Jul 1;16(1):5621. doi: 10.1038/s41467-025-60746-w. (IF=18.1，一作)
3. Weijie Xiong, Yixun Su*, Alexei Verkhratsky*, Chenju Yi*. Astrocytic Connexin43 in Alzheimer's disease: mechanisms, interaction with P2 receptors, and therapeutic potential. Neuropharmacology, 2026 Jan 01;282:110705. doi: 10.1016/j.neuropharm.2025.110705 (IF=4.7，并列通讯)
4. Yixun Su*, Alexei Verkhratsky*, Chenju Yi*. The Taming of the Shrew: Making Microglia Neuroprotective by Inhibiting Cx43 Hemichannels. Acta Physiol (Oxf). 2025 Sep;241(9):e70094. doi: 10.1111/apha.70094 (IF=5.7，一作并通讯)

2024

5. Su, Y., Verkhratsky, A.*, and Yi, C*. (2024). Targeting connexins: possible game changer in managing neuropathic pain? Trends in molecular medicine（封面文章）. 10.1016/j.molmed.2024.03.009. (IF=13.6，一作)
6. Huang, X.^#, Qi, J. ^#, Su, Y. ^#, Zhou, Y., Wang, Q., Huang, T., Xue, D., Zeng, Y., Verkhratsky, A., Zhou, B.*, Chen, H., Yi, C.* (2024). Endothelial DR6 in blood-brain barrier malfunction in Alzheimer's disease. Cell death & disease 15, 258. 10.1038/s41419-024-06639-0. (IF=12.2，并列一作) 
7. Yin, C.^#, Luo, K.^#, Zhu, X.^#, Zheng, R.^#, Wang, Y., Yu, G., Wang, X., She, F., Chen, X., Li, T., Chen, J., Bian, B., Su, Y.*, Niu, J.*, Wang, Y.* (2024). Fluoxetine rescues psychological behaviors in a murine PTSD model by alleviating excessive myelin formation. Neuroscience bulletin. (IF=5.6，并列通讯)

2023

8. Su, Y., Wang, X., Yang, Y., Chen, L., Xia, W., Hoi, K.K., Li, H., Wang, Q., Yu, G., Chen, X., Wang, S., Wang, Y., Xiao, L., Verkhratsky, A., Fancy, S.P.J.*, Yi, C.*, Niu, J.* (2023). Astrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during development. Neuron（封面文章） 111, 190-201.e198. 10.1016/j.neuron.2022.10.032. (IF=16.9，一作)

2022

9. Yu, G. ^#, Su, Y. ^#, Guo, C., Yi, C., Yu, B., Chen, H., Cui, Y., Wang, X., Wang, Y., Chen, X., Wang, S., Wang, Q., Chen, X., Hu, X., Mei, F., Verkhratsky, A., Xiao, L.*, Niu, J.* (2022). Pathological oligodendrocyte precursor cells revealed in human schizophrenic brains and trigger schizophrenia-like behaviors and synaptic defects in genetic animal model. Molecular psychiatry 27, 5154-5166. 10.1038/s41380-022-01777-3. (IF=11.0，并列一作)
10. Wang, Q. ^#, Huang, X. ^#, Su, Y., Yin, G., Wang, S., Yu, B., Li, H., Qi, J., Chen, H., Zeng, W., Zhang, K., Verkhratsky, A.*, Niu, J.*, Yi, C.* (2022). Activation of Wnt/β-catenin pathway mitigates blood-brain barrier dysfunction in Alzheimer's disease. Brain（封面文章） 145, 4474-4488. 10.1093/brain/awac236. (IF=14.5)

2021

11. Wang, Y. ^#, Su, Y. ^#, Yu, G., Wang, X., Chen, X., Yu, B., Cheng, Y., Li, R., Sáez, J.C., Yi, C.*, Xiao, L.*, Niu, J.* (2021). Reduced Oligodendrocyte Precursor Cell Impairs Astrocytic Development in Early Life Stress. Adv Sci (Weinh) 8, e2101181. 10.1002/advs.202101181. (IF=15.1，并列一作)
12. Wang, X. ^#, Su, Y. ^#, Li, T., Yu, G., Wang, Y., Chen, X., Yin, C., Tang, Z., Yi, C., Xiao, L., and Niu, J. (2021). Quetiapine promotes oligodendroglial process outgrowth and membrane expansion by orchestrating the effects of Olig1. Glia 69, 1709-1722. 10.1002/glia.23986. (IF=6.2，并列一作)
13. Huang, X. ^#, Su, Y. ^#, Wang, N., Li, H., Li, Z., Yin, G., Chen, H., Niu, J., and Yi, C. (2021). Astroglial Connexins in Neurodegenerative Diseases. Frontiers in molecular neuroscience 14, 657514. 10.3389/fnmol.2021.657514. (IF=4.8，并列一作)

2020

14. Su, Y., Zhang, W., Patro, C.P.K., Zhao, J., Mu, T., Ma, Z., Xu, J., Ban, K.*, Yi, C.*, and Zhou, Y.* (2020). STAT3 Regulates Mouse Neural Progenitor Proliferation and Differentiation by Promoting Mitochondrial Metabolism. Frontiers in cell and developmental biology 8, 362. 10.3389/fcell.2020.00362. (IF=5.5，一作)
15. Su, Y., Huang, X., Huang, Z., Huang, T., Xu, Y., and Yi, C.* (2020). STAT3 Localizes in Mitochondria-Associated ER Membranes Instead of in Mitochondria. Frontiers in cell and developmental biology 8, 274. 10.3389/fcell.2020.00274. (IF=5.5，一作)
16. Su, Y. ^#, Huang, X. ^#, Huang, Z., Huang, T., Li, T., Fan, H., Zhang, K.*, and Yi, C.* (2020). Early But Not Delayed Optogenetic RAF Activation Promotes Astrocytogenesis in Mouse Neural Progenitors. J Mol Biol 432, 4358-4368. 10.1016/j.jmb.2020.06.020. (IF=5.6，并列一作)

个人邮箱:

suyx27@mail.sysu.edu.cn