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李丹阳
硕士生导师、副研究员

个人简介:

 

伦敦玛丽女王大学生物医学材料博士,伦敦大学国王学院药学系Maplethorpe Fellow (成立以来首位中国女性获得者),硕士生导师,深圳市海外高层次人才。目前共主持国家级(2项),省级(1项),市级及其他(3项)科研项目共6项。发表高水平SCI论文50余篇,其中一作/通讯代表性论文包括有Nature CommunicationsAdvanced Science(封面),SmallBiosensors & Bioelectronics等。任ACS NanoAdvanced Functional MaterialsJournal of Controlled ReleaseBiomaterials等领域权威学术期刊的审稿工作,任BioNanoScience期刊编委,Journal of Visualized Experiments等期刊客座编辑。获2019年中国硬科技创新创业大赛一等奖,2020年深圳市创新创业大赛晋级决赛。近5年,以第一发明人申请发明专利5件,授权1件。参编专著3部,其中英文2部,教育部“十四五”规划教材1部。指导本科生获全国大学生基础医学创新研究实验室设计竞赛全国金奖+最佳团队合作奖,中山大学附属第七医院首届杰出教学奖获得者。

 

研究方向:

1.生物材料与生物界面、生物分子(核酸,蛋白等)之间的相互作用机制。

2.生物材料在肿瘤早期诊断,免疫治疗,再生医学中的研究。

3.细胞外囊泡的工程化及在疾病诊疗中的机制及应用研究。

 

近五年代表文:(#co-first authors, *corresponding author(s))

 

1. R. Cui#, H. Yang#, M. Kang*, D. Wang*, B. Tang*, D. Li*. Antibacterial hydrogel dressing with Ca2+-dependent hyaluronidase responsiveness for accelerating wound healing via on-demand release of AIE photosensitizers. Exploration, 2025.

2. X. Hao#, Y. Liu#, Y. Wen#, et al., D. Li*, L. Xu*. Two-pot ready-to-use reagents achieved quadruple-signal amplification for the ultra-sensitive biosensing of salmonella typhimurium in foods. Biosensors & Bioelectronics, 2025.

3. C. Hou#, S. Wang#, Z. Li#, et al., D. Li*, Y. Xu*. Curcumin-primed milk-derived extracellular vesicles remodel hair follicle microenvironment for the treatment of androgenetic alopecia. Regenerative Biomaterials, 2025.

4. X. Zhou#, B. Tang#, et al., L. Xu*, R. Ou*, Y. Xu*, D. Li*. Engineered mesenchymal stem cell‐derived extracellular vesicles scavenge self‐antigens for psoriasis therapy via modulating metabolic and immunological disorders. Advanced Science, 2025. (Cover story)

5. R. Cui, et al. L. Xu*, D. Li*. AI-assisted smartphone-based colorimetric biosensor for visualized, rapid and sensitive detection of pathogenic bacteria. Biosensors & Bioelectronics, 2024.

6. Z. Li#, X. Liu#, N. Cai#, et al., C. Zhang*, Z. Wei*, D. Li*. Immune checkpoint reprogramming via sequential nucleic acid delivery strategy optimizes systemic immune responses for gastrointestinal cancer immunotherapy. Cancer Letters, 2024.

7. Y. Liu#, P. Li#, et al., D. Li*, D. Shi*, L. Xu*. Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs)-based prototyping of integrated sensing devices for robust analysis. Trends in Analytical Chemistry, 2024.

8. Q. Wu, et al., L. Xu*, D. Li*. Photothermal ferrotherapy-induced immunogenic cell death via iron-based ternary chalcogenide nanoparticles against triple negative breast cancer. Small, 2024.

9. Q. Huang#, Y. Jiang#, Y. Cao#, et al., D. Li*, Q. Liu*, F. Li*. Bone-targeting engineered milk-derived extracellular vesicles for MRI-assisted therapy of osteoporosis. Regenerative Biomaterials, 2024.

10. J. Zhao, et al., D. Li*. Exosome-driven liquid biopsy for breast cancer: recent advances in isolation, biomarker identification and detection. Extracellular Vesicle, 2022.

11. R. Cui, et al., X. Zhan*, D. Li*. Polysaccharide-based hydrogels for wound dressing: design considerations and clinical applications, Front Bioeng Biotechnol, 2022. (Top cited paper)

12. A. Raynold#, D. Li#, et al., J. Gautrot*. Competitive binding and molecular crowding regulate the cytoplasmic interactome of non-viral polymeric gene delivery vectors. Nature Communications, 2021.

13. D. Li, et al., K. Al-Jamal*. Tailoring the architecture of cationic polymer brush modified carbon nanotubes for efficient siRNA delivery in cancer immunotherapy. ACS Applied Materials & Interfaces, 2021.

14. D. Li#*, L. Xu#, et al., Gautrot*. Responsive polymer brush design and emerging applications for nanotheranostics. Advanced Healthcare Materials, 2021.  

15. L. Xu#*, D. Li#, et al. Facile biosensors for rapid detection of COVID-19. Biosensors & Bioelectronics, 2020.

16. J. Wang, et al., D. Li*. Micro-patterned surface construction on BCP ceramics and the regulation on inflammation-involved osteogenic differentiation. Materials & Engineering C, 2020.

17. J. Wang, et al., D. Li*. Fabrication and preliminary evaluation of the osteogenic potential for micro-/nano-structured porous BCP ceramics. Ceramics International, 2020.

 

参编专著:

  1.吴强#,崔荣伟#李丹阳*。《纳米生物医药学》。第四章 药用生物材料与纳米载体。化学工业出版社,2025.

2. D. Li, K. Al-Jamal*. Design and delivery of siRNA therapeutics. Chapter 12 SiRNA design and delivery based on carbon nanotubes. H.J. Ditzel, M. Tuttolomondo, S. Kauppinen (Eds.), Methods in Molecular Biology, 2021.

3. D. Li, J. Gautrot*. Polymer and Biopolymer Brushes. Chapter 20 Design of polymer brushes for cell culture and cellular delivery: for materials science and biotechnology. Wiley, December, (2) 2017, 557-603.  

  

招生信息:

报考专业:分子医学(大类:基础医学);要求背景:基础医学、分子生物学、药学、材料学、化学等;希望性格开朗,阳光积极,有良好的英文听说读写能力,有良好的学术训练。

 

招聘信息:

招聘岗位:研究实习员

学历要求:硕士/博士

专业要求:基础医学,生物医学工程,药学等相关专业,从事过于本课题组研究方向相符合的课题

其他要求:品行端正,为人正直,性格开朗,无不良记录,有良好的科研思维,受过良好的科研训练和一定的科研追求,有独立完成至少一个课题的科研经历,发表过至少一篇第一作者(不含共同)SCI论文,有良好的英文听说读写水平,除本身课题外,能协助课题组PI完成日常的课题组管理工作。

待遇福利:待遇丰厚,具体面谈,可申请单位住房,协助子女入学入托等其他福利。

申请方式:请将个人简历+代表作+毕业论文+推荐人联系方式,打包发送至lidy55@mail.sysu.edu.cn,邮件名称注明:研究实习员应聘+单位+姓名

 

联系邮箱:

lidy55@mail.sysu.edu.cn

出诊信息